Inspektor Research Systems

Whitepaper on QLF™

This whitepaper provides background information on the technology, discusses its practical use and highlights the status of current research.


A very interesting study by Monique van der Veen e.a. from ACTA, Amsterdam, Netherlands. This paper shows the association between red fluorescent plaque revealed by QLF™ after 24 h plaque accumulation and inflammatory response after a prolonged period of no oral hygiene. Red plaque fluorescence can be used to identify subjects at risk for developing gingival inflammation:

Dynamics of red fluorescent dental plaque during experimental gingivitis-a cohort study (new!)

Below the most recent papers on various aspects of QLF™ by members of the group of Prof. Baek-Il Kim, Yonsei University, Seould, South Korea:

Explaining the Red Fluorescence Evident on the Surface of Failed Dental Implants (new!)
Ecological changes in oral microcosm biofilm during maturation
Assessing the use of Quantitative Light-induced Fluorescence-Digitalas a clinical plaque assessment
Differences in the intensity of light-induced fluorescence emitted byresin composites
Validity and reliability of autofluorescence-based quantificationmethod of dental plaque
Clinical assessment of malodor with QLF
An in vitro comparison of QLF and spectrophotometer on monitoring artificial white spot lesions

A paper, from Turkey, showing the use of QLF™ to compare the development of white spot lesions in patients that received orthodontic treatment with full coverage rapid maxillary expanders compared to patients that recieved no orthodontic treatment.

White spot lesion formation after treatment with full-coverage rapid maxillary expanders

Very slowly, the advantages of QLF™ for the daily clinical practice are reaching the work floor: see this article in the (Dutch) Dental Herald Tribune where ACTA professor Cor van Loveren speaks out for dental diagnostic tools:

Huidige systeem staat gezonde mond in de weg.

This scientific publication, validating the ability of QLF™ to detect caries and approximal caries in particular, is from Hae-Youn Ko from the group of Prof. Baek-Il Kim if Yonsei University, Seoul, South Korea:

Validation of QLF for the detection of approximal caries in vitro

A very interesting thesis about the positive effects of Non-Operative Caries Treatment and Prevention by Erik Vermaire (2013) can be downloaded through the following link:

Optimizing Oral Health, Vermaire J.H., 2013

Good examples of the kind of research that can be done with the QLF-D Biluminator™ are the following articles, published in the American Journal of Dentistry 26(3): 132-136 and the on-line version of the Journal of Dentistry respectively, from the group of Prof. Baek-Il Kim of Yonsei University where the link is investigated between remineralization rates and severity of early lesions and cariogenic levels of biofilm and the intensity of red fluorescense:

Monitoring the maturation process of a dental microcosm biofilm using the Quantitative Light-induced Fluorescence-Digital (QLF-D)

Recovery percentage of remineralization according to severity of early caries

Association between the cariogenicity of a dental microcosm biofilm and its red fluorescence detected by Quantitative Light-induced Fluorescence-Digital (QLF-D)


Below are a few more links related to research and use of QLF:


Introduction to QLF


QLF at the University of Liverpool

QLF at the UT Health Science Center of San Antonio

QLF in Russia


QLF and fluorosis

QLF and stains

QLF at the Medical Futures in London


Flexible arms for the dental Clinic

Explanation of caries

QLF clip